Monthly Research Review – January 2016

The end of 2015 has seen a total 4,189 autism research papers published and listed on PubMed. This is a 28% increase in autism research papers published over the last 12 months from 2014. This is why unless you are looking at ASD research regularly, you will be missing how we understand ASD and the treatments that are improving ASD children’s lives.

Many biomedical treatments that parents have been using to treat their children over many years are being shown by current studies to be promising “new” treatments for ASD children.

Use and Perceived Effectiveness of Complementary and Alternative Medicine to Treat and Manage the Symptoms of Autism in Children: A Survey of Parents in a Community Population. Anecdotal evidence continues to confirm that Complementary and Alternative Medicine (CAM) is beneficial in dealing with the health and behavioural issues in ASD children. These are most effective while they are still young and building the foundation for their future years.

Hair Heavy Metal and Essential Trace Element Concentration in Children With Autism Spectrum Disorder. This helps validate why chelation therapy has been reported, via the ARI parent survey, to be beneficial for up to 73% of ASD children.

Zn/Cu Levels in the Field of Autism Disorders: A Systematic Review and Meta-analysis.Full text. Measuring zinc and copper levels in ASD children has been one of the most basic tests that is performed by biomedical practitioners treating ASD children. Although this study refers to Zn/Cu ratios, more typically they are expressed as Cu/Zn ratios. Again parents should take note that the research is validating what the biomedical community has been doing for years.

Targeting Glia with N-Acetylcysteine Modulates Brain Glutamate and Behaviors Relevant to Neurodevelopmental Disorders in C57BL/6J Mice. Full text.

Dietary docosahexaenoic acid alleviates autistic-like behaviors resulting from maternal immune activation in mice.

Beneficial action of resveratrol: How and why?

Perinatal Phosphatidylcholine Supplementation and Early Childhood Behavior Problems: Evidence for CHRNA7 Moderation. This is a very interesting study. If there is a family history of autism, supplementation with phosphatidylcholine may be warranted.

As ASD children grow into adults, the research is now showing us the huge issues that these young adults face as they enter adulthood. It is important for parents to look at these studies and be aware that this may happen to their child. Many parents are complacent, especially if their children are high functioning, that their children will be able to function independently. However, the research is showing us that they also have many issues that they need to deal with. Some are quite unexpected.

Therapeutic and Ethical Dilemma of Puberty and Menstruation Problems in an Intellectually Disabled (Autistic) Female: a Case Report.

Evaluation of Asperger Syndrome in Youth Presenting to a Gender Dysphoria Clinic.

Alexithymia in Adolescents with Autism Spectrum Disorder: Its Relationship to Internalising Difficulties, Sensory Modulation and Social Cognition.

Testosterone in relation to behavioral problems in pre-pubertal boys with autism spectrum disorders. Full text.

Driving Simulator Performance in Novice Drivers with Autism Spectrum Disorder: The Role of Executive Functions and Basic Motor Skills.

An Autistic Endophenotype and Testosterone Are Involved in an Atypical Decline in Selective Attention and Visuospatial Processing in Middle-Aged Women.Full text.

More studies are looking at the possible causes of ASD. Mother’s are always worried about subsequent pregnancies and possibility having a subsequent ASD child. The better we understand the possible causes, we may be able to advise mothers on how to minimise the risk for subsequent pregnancies.

Antidepressant Use During Pregnancy and the Risk of Autism Spectrum Disorder in Children.

Maternal use of acetaminophen during pregnancy and risk of autism spectrum disorders in childhood: A Danish national birth cohort study.

Poor Brain Growth in Extremely Preterm Neonates Long Before the Onset of Autism Spectrum Disorder Symptoms.

Developmental Neurotoxicity of Inhaled Ambient Ultrafine Particle Air Pollution: Parallels with Neuropathological and Behavioral Features of Autism and Other Neurodevelopmental Disorders.

For more research into ASD that your medical professional is not reading. Just follow the link to my Autism page, and scroll down to Current Research – Selected research articles of interest.

Be informed, NOT misinformed!